Clinical study of the efficacy and safety of jamu for hyperuricemia

Agus Triyono, Fajar Novianto


Abstract


Hyperuricemia is a degenerative disease with a reasonably high prevalence and requires long-term treatment. Clinical research has been conducted to test the efficacy and safety of herbal medicine for hyperuricemia. The research involved 30 subjects who had fulfilled the inclusion and exclusion criteria and conducted with a pre-post test research design. Subjects were treated with herbal medicine for hyperuricemia three times a day for 28 days. From the research, jamu for hyperuricemia was effective in reducing blood uric acid levels from 7.43 mg/dL to 5.72 mg/dL, raising the quality of life score (SF-36) from 78.06 to 81.50, and disappeared of clinical symptoms. Use of herbal medicine for hyperuricemia for 28 days in subjects had no symptoms of severe side effects found and did not interfere with liver, kidney, and blood function.

Keywords


clinical research; jamu; hyperuricemia

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References


Afifah, E. & Lentera, T. (2003). Khasiat & manfaat temulawak: rimpang penyembuh aneka penyakit. Jakarta, Indonesia: Agromedia. Anggraeni, R. A. (2013). Uji Aktivitas Antihiperurisemia Ekstrak N-Heksana, Etil Asetat Dan Etanol 70% Daun Kepel [Stelechocarpus Burahol (Bi.) Hook. F. & Th.] Pada Mencit Putih Jantan Hiperurisemia. (Undergraduate thesis, Universitas Jember, Jember, Indonesia). Retrieved from http://repository.unej.ac.id/handle/123456789/2563. Cendrianti, F., Muslichah, S., & Ulfa, E. U. (2014). Uji Aktivitas Antihiperurisemia Ekstrak n-Heksana, Etil Asetat, dan Etanol 70% Daun Tempuyung (Sonchus arvensis L.) pada Mencit Jantan Hiperurisemia. Pustaka Kesehatan, 2(2), 205-210. Kementrian Kesehatan. (2010). Peraturan Menteri Kesehatan Republik Indonesia Nomor: 003/MENKES/PER/I/2010 tentang Saintifikasi Jamu dalam Penelitian Berbasis Pelayanan Kesehatan. Jakarta, Indonesia: Author. Lamb, E., Newman, J, D., & Price, P, C. (2006). Kidney Function Test In C. Burtis., E. Ashwood & D. Bruns (Eds.), Tietz Textbook of Clinical Chemistry and Molecular Diagnostic 4th edition (pp. 803-805). Philadelphia, PA: Elseiver Saunders. McGilvery, R. W., & Golstein, G. W. (1996). Biokimia Suatu Pendekatan Fungsional Edisi Ketiga. Surabaya, Indonesia: Airlangga University Press. Nurwanto, A. H. (2013). Efek Analgesik Dekok Rimpang Kunyit (Curcuma Domestica Val.) Pada Tikus Putih Strain Wistar Dengan Metode Paw Pressure Test. (Doctoral dissertation, University of Muhammadiyah Malang, Malang, Indonesia). Retrieved from http://eprints.umm.ac.id/28423. Pertamawati & Hardhiyuna M. (2015). Uji Penghambatan Aktivitas Enzim Xantin Oksidase Terhadap Ekstrak Kulit Kayu Secang (Caesalpinia sappan L.). Kartika : Jurnal Ilmiah Farmasi, 3(2), 12-17. Singh, V., Gomez, V, V., & Swamy, S, G. (2010). Approach to a Case of Hyperuricemia. Indian Journal of Aerospace Medicine, 54(1), 40-45. Soenarta & Arieska. (2005). Konsensus pengobatan hiperurisemia. Jakarta, Indonesia: Perhimpunan Hiperurisemia Indonesia. Sudoyo, A. W. (2006). Buku Ajar Ilmu Penyakit Dalam Jilid II Edisi IV. Jakarta, Indonesia: Departemen Ilmu Penyakit Dalam FKUI. Winarno, M. W., Widowati, L., & Sundari, D. (2015). Studi keamanan ramuan jamu untuk hiperurisemia dan hipertensi. Buletin Penelitian Kesehatan, 43(3), 137-146.




DOI: https://doi.org/10.22219/farmasains.v4i1.6628 | Abstract views : 154 | PDF views : 11

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