Enhancement Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression of Macrobrachium rosenbergii Fed With Aqueous Morinda citrifolia Leaves Extract-Supplemented Diet

Atika Marisa H, Arief Prajitno, Chin Chyuan Chang


Morinda citrifolia, known commercially as noni is often used for enhance immunity, these plant rich of phenolic compound with antioxidant properties. In the present study, Macrobrachium rosenbergii were fed with diets containing of aqueous M. citrifolia leaves extract (AMLE) at 0.6, 4 and 6 g kg-1. Glutathione peroxidase (GPx) activity was conducted to measure immune parameter, these parameter was evaluated before and after 7, 21, 35, 49 and 63 days of feeding trial. Immune gene expression of α2-macroglubulin (α2-M) was evaluated in this study. The results showed that after 63 days of feeding treatment, significantly increased in GPx activity. Gene expressions of α2-macroglubulin was significantly upregulated. These results recommend that administration of AMLE can be used as an immunostimulant and regulated immune response and immune gene expression in M. rosenbergii.


Keyword: Morinda citrifolia, Macrobrachium rosenbergii, GPx, α2-M

DOI: https://doi.org/10.22219/IOJAUMM.Vol1.No1.31-40


  • There are currently no refbacks.

Editorial Office 
Aquaculture Department, Faculty of Agriculture and Animal Science, University of Muhammadiyah Malang
Jl. Tlogomas No 246 Malang, Jawa Timur, Indonesia 
Phone (+62) 341464318 ext 222

email : ioja@umm.ac.id

View My Stats Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.