Synapsis Expression Increased By Mozart’s Music Stimulation Compared With Indonesian Pop And Religious Music

Authors

  • Ukhti Mukminah ilmi Amila Airlangga University
  • Hermanto Tri Joewono Airlangga University
  • Widjiati Widjiati Airlangga University

DOI:

https://doi.org/10.22219/sm.Vol16.SMUMM1.10784

Keywords:

Mozart, pop, religious, Synapsin

Abstract

Classical music stimulation is a proven method that affect intelligence as well as brain function. Mozart’s classical music is classical music that could stimulate the growth of synaptic networks. To analyze the difference of synapsin expression of the brain of Rattus norvegicus  offspring on Mozart’s, pop, religious and without music stimulation during pregnancy. Experimental. Treatments were subjected to Rattus norvegicusas a subject organism, initiated on the 10th day of pregnancy, in 1 hour duration in a soundproof chamber, intensity of 65 dB. On the 19th day of pregnancy the subjects were sacrificed and three offsprings were chosen. The head of the chosen Rattus norvegicusoffsprings were decapitated and the brain subsequently sectioned to calculate synapsin expression by immunohistochemistry method with 400 magnification strength microscope on the 5 field of view. Significant difference of synapsin expression of the brain of Rattus norvegicus offspring was observed between Mozart’s and control group. Significant differences of synapsin expressions were observed in the cerebellum of the newly born Rattus novergicus between Mozart and pop music groups (p = 0,007), Mozart and religious music groups (p = 0,008), Mozart and without music groups (p = 0,004).Synapsin expression of Rattus norvegicus brain offsprings were higher in Mozart music stimulation compared with pop and religious music stimulation

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Author Biographies

Ukhti Mukminah ilmi Amila, Airlangga University

Ilmu Kesehatan Reproduksi Fakultas Kedokteran Universitas Airlangga

Hermanto Tri Joewono, Airlangga University

Obstetri dan Ginekologi Fakultas Kedokteran Universitas Airlangga – RSUD Dr. Soetomo Surabaya

Widjiati Widjiati, Airlangga University

Departemen Anatomi Veterenier Fakultas Kedokteran Hewan Universitas Airlangga

References

Gabriel JF. 1988. Fisika Kedokteran. Penerbit Buku Kedokteran EGC, Jakarta. Hal: 65-98 Hermanto TJ, Estoepangesti ATS dan Widjiati. 2002. The influence of musical exposure to pregnant (Rattus Novergicus) Rat to the amount of neonatal rat brain cells. Abstract of the 3rd Scientific meeting on Fetomaternal Medicine and AOFOG Accredited Ultrasound Workshop. 2002: 31. ________ . 2004. Smart babies through Prenatal University Mission Impossible. Majalah Obstetri dan Ginekologi Indonesia, 28(1):14. ________ . 2012. Bersujud dalam Rahim 2, Mencerdaskan Janin sejak dalam Rahim dengan KombinasiStimulasi 11 – 14 Musik Mozart dan Nutrisi. Global Persada Press. Surabaya Ji, Y., Pang, P.T., Feng L., and Lu B. 2005. Cyclic AMP controls BDNF-induced TrkB phosphorylation dan dendritic spine formation in mature hippocampal neurons. Nat Neurosci.;8:164–172. Parncutt R, 2006. Prenatal Development. Mc Pher chap 01: 1-22 Rees, S., and D. Walker. 2001. Nervous and Neuromuscular System. In Harding R. Bocking AD. Fetal Growth and Development. Cambridge, United Kingdom: Cambridge University Press. (1st). United Nations Development Programme [UNDP]. 2018. Human Development Indices and Indicators 2018 Statistical Update. New York.

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Published

2020-06-27

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