PENGARUH PEMBERIAN KOPI TERHADAP PENURUNAN KADAR GLUKOSA DARAH PADA TIKUS PUTIH STRAIN WISTAR DIABETES MELLITUS TIPE 2
DOI:
https://doi.org/10.22219/sm.v9i1.4124Abstract
Penilitian ini bertujuan untuk membuktikan pengaruh kopi terhadap penurunan kadar glukosa darah pada tikus putih strain wistar diabetes mellitus tipe 2.penelitin ini menggunakan metode eksperimen laboratoris rancangan the post test only control group desain. Sampel tikus putih strain wistar dibagi 4 kelompok. Sampel I : kontrol negatif, II: kontrol positif, dua kelompok lainnya diberikan kopi Robusta berbagai dosis (5,4 mL/200 gr BB/ hari, 10,8 mL/200 gr BB/hari). Analisis data menggunakan One Way Anova, uji Tukey 5%, uji korelasi dan uji regresi linier. Hasil uji One Way Anova terdapat pengaruh perlakuan dengan perbedaan yang bermakna terhadap penurunan kadar glukosa darah. Dari uji korelasi terdapat korelasi yang berbanding lurus dan sangat bermakna antara dosis kopi dan jumlah penurunan kadar glukosa darah tikus putih diabetes mellitus tipe 2 dengan nilai Pearson Correlation -0,978 pada glukosa darah puasa dan -0,932 pada glukosa darah 2 jam post pandrial, sedangkan hasil uji regresi didapatkan nilai R2 = 0,956 pada glukosa darah puasa dan 0,869 pada glukosa darah 2 jam post pandrial. Kesimpulan : Pemberian kopi berbagai dosis dapat menurunkan kadar glukosa darah tikus diabetes mellitus tipe 2.
Kata kunci : diabetes mellitus tipe 2, kadar glukosa darah, kopi Robusta
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