PENGARUH PEMBERIAN MINUMAN BERENERGI SUBAKUT TERHADAP GAMBARAN HISTOLOGI GINJAL TIKUS PUTIH STRAIN WISTAR

Authors

  • Utari Prasetyaning
  • Desy Andari
  • SM Agustini

DOI:

https://doi.org/10.22219/sm.v9i1.4125

Abstract

Penelitian ini bertujuan untuk membuktikan adanya pengaruh pemberian minuman berenergi subakut terhadap gambaran histologi ginjal tikus putih strain wistar. Metode : Eksperimen laboratoris dengan rancangan the post test only control group design. Sampel dibagi dalam 4 kelompok. Kelompok I (K) tanpa pemberian minuman berenergi,kelompok II. III dan IV (P1, P2, P3) diberikan minuman berenergi 72 mg, 216 mg dan 360 mg. Analisis data menggunakan One Way Anova, uji Tukey, uji korelasi dan uji regresi. Hasil : Hasil uji One Way Anova dan uji Tukey didapatkan nilai sig=0,000 (p<0,05) artinya terdapat pengaruh yang signifikan antara perlakuan dengan jumlah sel nekrosis dan terdapat perbedaan yang bermakna antar kelompok. Hasil uji korelasi dan regresi didapatkan r=0,988 dan R2=0,976 artinya semakin tinggi dosis akan diikuti oleh peningkatan jumlah sel nekrosis. Kesimpulan : Minuman berenergi dapat meningkatkan jumlah sel nekrosis pada sel epitel tubulus proksimal ginjal.

Kata kunci : Minuman berenergi, kafein, histologi ginjal, nekrosis sel epitel tubulus proksimal ginjal

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Published

2017-03-20

Issue

Vol. 9 No. 1 (2013): Juni 2013

Section

Article

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