The Relationship Of Alcohol Consumption, Smoking, And Body Mass Index On The Occurrence Of Triple Negative Breast Cancer: Meta-Analysis

Authors

  • Agiel Jelang UMM
  • Dian Yuliartha Lestari
  • Gita Sekar Prihanti
  • Anung Putri Illahika

DOI:

https://doi.org/10.22219/apisio.Vol2.AM1.31742

Keywords:

Alcohol, Smoking, Body Mass Index, TNBC

Abstract

Triple Negative Breast Cancer (TNBC) is a type of cancer that is negative for the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2. Symptoms include swelling of all or part of the breast, skin dimpling, breast or nipple pain, retraction. nipples, red, dry, peeling or thickened nipple or breast skin, nipple discharge, swollen lymph nodes under the arms or near the collarbone. This research is a systematic review study with Meta Analysis using PRISMA guidelines. Alcohol drinkers are at greater risk of TNBC than non-alcohol drinkers (RR=3.17; 95% CI: 2.09-2.55; p = 0.0006), non-smokers are at greater risk of TNBC (RR=0.22; 95% CI: 0.14- 0.33; p = 0.00001), the relationship between people with BMI>25 and BMI<25 who had TNBC was not statistically significant (RR=1.02; 95% CI: 0.85-1.23; p = 0.83). Alcohol consumption has an effect on the occurrence of TNBC, non-smokers have an effect on the occurrence of TNBC, there were no significant results between BMI>25 and BMI<25 on the occurrence of TNBC.

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References

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Published

2024-02-25

Issue

Vol. 2 No. 1 (2024): February 2024

Section

Articles

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