Potential Combination of Wuluh Starfruit (Averrhoa bilimbi L.) and Clove (Syzygium aromaticum) Extract Gel for Incision Wound Healing

Joevan Jusuf Bachtiar; Mochamad Aleq Sander

doi:10.22219/apisio.Vol1.AM2.42310

Authors

Joevan Jusuf Bachtiar Universitas Muhammadiyah Malang
Mochamad Aleq Sander

DOI:

https://doi.org/10.22219/apisio.Vol1.AM2.42310

Abstract

Background: Incision wounds are usually caused by an incision in the skin and underlying tissue by a sharp, sterile or non-sterile instrument. The potential use of herbal ingredients as medicine is believed to have the advantage of minimal side effects. Supported by Indonesia's geographical conditions, which have a tropical climate with fertile nature and have many TOGA (Family Medicinal Plants), even plants which are cooking spices such as starfruit (Averrhoa bilimbi L.) and cloves (Syzygium aromaticum) have the potential to be used as an antibacterial and anti-inflamation agent on incision wound. Method: A Literature review by taking information from 23 journals and 1 textbook. Journals were obtained from the search engines Google Scholar and PubMed NCBI. The data and information obtained are processed to support the research objectives. Result: Infection of the incision wound can be caused by exposure to bacteria from instruments and non-sterile materials that touch the wound. Phenolic compounds in the extract of wuluh starfruit (Averrhoa bilimbi L.) and cloves (Syzygium aromaticum) act as antibacterial agents and anti-inflammatory agent that reduce levels of inflammatory mediator cytokines, namely IL-1β, IL-6, TNF-α significantly. The high water content in the gel assists in tissue granulation and epithelialization in moist conditions. Conclusion: Combination of wuluh starfruit (Averrhoa bilimbi L.) and clove (Syzygium aromaticum) extract gel have the potential to heal incision wounds

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