Correlation between Diabetes Melitus Type II and knee Oosteoarthritis in Wahiddin Sudirohusodo Hospital
DOI:
https://doi.org/10.22219/sm.Vol16.SMUMM1.10654Keywords:
osteoarthritis, diabetes mellitusAbstract
This research is aimed to find out the correlation between Diabetes Mellitus Type II and the incidence of knee osteoarthritis in Wahiddin Sudirohusodo Makassar Hospital.
This research was a case-control conducted on outpatients in the Orthopedic Division of the Department of Surgery, Wahiddin Sudirohusodo General Hospital. There were 51 cases and 51 controls were randomly selected using secondary data from medical records in the period of May 2017 to May 2018.
The results indicate that the patients have an average age of 55.15 + 8.78 years with the majority female gender of 72 people (70,6%). The patient had a mean blood sugar level of 195,84 + 83,4. Bivariate analysis between knee OA and DM type II obtained the value of Odd Ratio i.e. OR = 4.320 (95% Confidence Interval 1.791-10.425). There is a significant correlation between knee osteoarthritis and type II DM with the incidence of knee osteoarthritis (p = 0.002). Type II Diabetes Mellitus increases the risk 4 times to knee osteoarthritis OR = 4.320 (95% Confidence Interval 1.791-10.425).Downloads
References
Bay-Jensen, A.C. Slagboom, E. Chen-An, P. Alexandersen, P. Qvist, P.Christiansen, C. Meulenbelt, I. Karsdal, M.A. 2012. Role of hormones in cartilage and joint metabolism: understanding an unhealthy metabolic phenotype in osteoarthritis. Menopause. 20 (5) : 578-586
Bennell, K.L and Hinman, R.S. 2011. A review of the clinical evidence for exercise in osteoarthritis of the hip and knee. Journal of Science and Medicine in Sport. 14: 4-9
Cubukcu, D. Sarsan, A. Alkan, H. 2012. Relationship between Pain, Function and Radiographic Findings in Osteoarthritis of the Knee: A Cross-Sectional Study. Arthritis.1-5
Kohei, K. 2010. Pathophysiology of type 2 diabetes and its treatment policy. JMAJ.53 (1) ; 41-46
Mahajan, A. Verma, S. Tandon, V. 2005. Osteoarthritis. JAPI. 53: 634-641
Onur, T. Wu, R. Metz, L. Dang, A. 2014. Characterization of osteoarthritis in a small animal model of type 2 diabetes mellitus. Bone Joint Res. 3: 203-2011
Ozougwu, J.C. Obimba, K.C. Belonwu, C.D. Unakalamba, C.B. 2013. The pathogenesis and pathophysiology of type 1 and type 2 diabetes mellitus. Journal of Physiology and Pathophysiology. 4(4) : 46-57
Paradowski, P.T. 2014. Osteoarthritis of the Knee: Assessing the Disease. Health Care Current Reviews. 2 (2): 1-4
PERKENI. 2011. Konsensus Pengelolaan dan Pencegahan Diabetes Mellitus tipe 2 di Indonesia. Jakarta: Pengurus Besar Perkumpulan Endokrinologi Indonesia
Plaza, M.M. Santana, L.E.C. Font, Y.M. Mayor, A.M, Vila, L.M. 2013. Association of hand or knee osteoarthritis with diabetes mellitus in a population of Hispanic from Puerto Rico. J. Clin. Rheumatol. 19 (1) : 1-16
Pottie, P. Presle, N. Terlain, B. Netter, P. Mainard, D. Berenbaum, F. 2015. Obesity and osteoarthritis: more complex than predicted! Obesity and osteoarthritis.1403-1407
Purnamasari, D. 2014. Diagnosis dan klasifikasi Diabetes Mellitus. Buku Ajar Ilmu Penyakit Dalam. Interna Publishing. Jakarta: 2323-2327
Rasjad, C. 2007. Kelainan Degeneratif Tulang dan Sendi. Pengantar Ilmu Bedah Ortopedi. Yarsif Watampone. Jakarta: 196-219
Rizaldi, M.B. 2014. Karakteristik penderita osteoartritis lutut di RSUP Haji Adam Malik Medan.
Roach HI, Tilley S. 2007. The Pathogenesis of Osteoarthritis. In: Bronner F, Carson M, editors. Bone and Osteoarthritis. Vol 4. Springer. USA: 1-27
Schett, G. Kleyer, A. Perricone, C. Sahinbegovic, E. Iagnocco, A. Zwerina, J.Lorenzini, R. Aschenbrenner, F. Berenbaum, F. D’Agostino, M.A. Willeit, J. Kiechi, S. 2013. Diabetes Is an Independent Predictor for Severe Osteoarthritis. Diabetes Care. 36: 403-410
Shen, J, and Chen, D. 2014. On the Horizon From the ORS. J Am Acad Orthop Surg. 22: 467-468
Utama, H. 2009. Penatalaksanaan Diabetes Mellitus Terpadu. Edisi 2. Balai Penerbit FKUI: Jakarta
Wild, S. Roglic, G. Green, A. Sicree, R. King, H. 2004. The global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 27: 1047-1053
WHO. 2004. The Global Burden of Disease 2004 Update. Tersedia di: http://www.who.int/healthinfo/globall_burden_disease/GBD_report_2004 update_full.pdf?ua=1. Diakses pada 12 Agustus 2017
Wood, A.M. Brock, T.M. Heil, K. Holmes, R. Weusten, A. 2013. A review on the management oh hip and knee osteoarthritis. International Journal of Chronic Disease.
Downloads
Published
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
