Efficacy of Osteoporosis Drugs Anabolic and Antiresorptive Classes in Post Menopause Women
DOI:
https://doi.org/10.22219/sm.Vol17.SMUMM2.15595Abstract
Osteoporosis is a degenerative bone disease that affects many postmenopausal women. Antiosteoporosis drugs consist of antiresorptive and anabolic groups. So far, there is still controversy over the administration of antiosteoporosis drugs, therefore researchers conducted a systematic review study aimed at determining which one is more effective. This research was conducted by reviewing several studies through the PubMed and Science Direct databases. The results showed that abaloparatide, teriparatide, and SERM (Selective Estrogen Receptor Modulators) were more effective than bisphosphonates. In conclusion, the anabolic class is more effective than the antiresorptive class in postmenopausal women.
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An, Ki-Chan. Selective Estrogen Receptor Modulators [Internet]. NCBI. 2016 [cited 6 January 2021]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995266/
Bethel, Monique. Osteoporosis [Internet]. Medscape. 2019 [cited 24 July 2020]. Available from: https://emedicine.medscape.com/article/330598-medication
Bilotta, G., Milner, A. and Boyd, I. Quality assessment tools for evidence from environmental science. Environmental Evidence. 2014;3(1):p.14. https://doi.org/10.1186/2047-2382-3-14
Cai, Shaofang et al. Bone Mineral Density and Osteoporosis in Relation to All-Cause and Cause-Specific Mortality in NHANES: A Population-Based Cohort Study. Bone Elsevier. 2020. https://doi.org/10.1016/j.bone.2020.115597
Chen, Xiao et al. Osteoblast-Osteoclast Interactions [Internet]. NCBI. 2017 [cited 21 August 2020]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612831/
Gorter, E. A. et al. Does osteoporosis affect the healing of subcapital humerus and distal radius fractures?. Journal of Orthopaedics. 2020;pp.237-241. https://doi.org/10.1016/j.jor.2020.05.004
Hartiningsih and Anggraeni, D. Suplementasi Calcitriol Menurunkan Risiko Osteoporosis Tikus Ovariektomi. Jurnal Sain Veteriner. 2015;33(2). https://issn.org/0126-0421
Hidayati, R. Sistem Pakar Untuk Penentuan Terapi Pada Penderita Osteoporosis. Jurnal Informatik aUpgris. 2019;5(1). https://doi.org/10.26877/jiu.v5i1.3608
Humaryanto, H. Deteksi Dini Osteoporosis Pasca Menopause. Jambi Medical Journal. 2017;5(2):pp.164-177.
Kawiyana, I. Osteporosis Patogenesis Diagnosis Dan Penanganan Terkini. Journal of Internal Medicine. 2009;10(2).
Kementerian Kesehatan RI. Pusat Data dan Informasi Kementerian Kesehatan RI: Data dan Kondisi Penyakit Osteoporosis di Indonesia [Internet]. Kementerian Kesehatan RI. 2015 [cited 20 July 2020]. Available from: www.kemkes.go.id
Kessenich, Cathy R. Osteoporosis and African-American Women. Womens Health Issues. 2000. https://doi.org/10.1016/S1049-3867(00)00065-7
Kristiningrum, E. Farmakoterapiuntuk Osteoporosis. Continuing Medical Education. 2020;47:pp.41-48.
Liberati, A. et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Journal of clinical epidemiology. 2009. https://doi.org/10.1016/j.jclinepi.2009.06.006
M., Nursalam et al. PedomanPenyusunanSkripsi-Literature Review danTesis-Systematic Review. FakultasKeperawatanUniversitasAirlangga. 2020;pp.1-118.
Marozik, P. et al. Bone metabolism genes variation and response to bisphosphonate treatment in women with postmenopausal osteoporosis. PLoSONE. 2019;14(8):pp.1-14. https://doi.org/10.1371/journal.pone.0221511
McClung, M. R. et al. Effects of abaloparatide on bone mineral density and risk of fracture in postmenopausal women aged 80 years or older with osteoporosis. Menopause. 2018;25(7):pp.767-771. https://doi.org/10/1097/GME.0000000000001080
Nasomyont, N. et al. DMD-THERAPY: P.293 Safety and Efficacy of Teriparatide Treatment for Severe Osteoporosis in Patients with Duchenne Muscular Dystrophy. Neuromuscular Disorders. 2020. https://doi.org/10.1016/j.nmd.2020.08.290
Pouresmaeili, Farkhondeh et al. A Comprehensive Overview On Osteoporosis and Its Risk Factors [Internet]. NCBI. 2018 [cited 21 August 2020]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225907/
Resnasari, S. D., Supartono, B. and Ekapurwani, L. The Correlation Between Low Body Mass Index (Underweight) With Bone Strength On Elderly Women. Jurnal Saintika Medika. 2020;pp.14-20. doi:10.22219/sm.Vol16.SMUMM1.10598
Riggs, B. L. Overview of Osteoporosis. Rochester, Minnesota: Western Journal of Medicine; 1991.
Saag, K. G. et al. Effect of Abaloparatide on Bone Mineral Density and Fracture Incidence in a Subset of Younger Postmenopausal Women with Osteoporosis at High Risk for Fracture. Clinical Therapeutics. 2020;42(6):pp.1099-1107.e1. https://doi.org/10.1016/j.clinthera.2020.04.012
Shin, C. J. et al. Effectiveness of Osteoporosis Drug in Postmenopausal Women with Spinal Compression Fracture: Combined Consecutive Therapy of Teriparatide and Raloxifene versus Bisphosphonate Single. Korean Journal of Neurotrauma. 2016;12(2):p.123. https://doi.org/10.13004/kjnt.2016.12.2.123
Supartono, B. dkk. Bunga Rampai Kesehatan Olahraga. Jakarta: Rumah Sakit Olahraga Nasional Kementerian Pemuda dan Olahraga; 2015.
The Joanna Briggs Institute. Checklist for Cohort Studies and Randomized Controlled Trials. Joanna Briggs Institute Critical Appraisal tools. 2020.
Tu, Kristie et al. Osteoporosis: A Review of Treatment Options [Internet]. NCBI. 2018 [cited 6 January 2021]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768298/
Upadhyaya, G. K. et al. Challenges and strategies in management of osteoporosis and fragility fracture care during COVID-19 pandemic. Journal of Orthopaedics. 2020;pp.287-290. https://doi.org/10.1016/j.jor.2020.06.001
Waseso, L. B., Supartono, B. and Fauziah, C. Physical Activity and The Strength of Bone in Menopause Patients in National Sports Hospital in 2017. Berkala Kedokteran. 2018;14(1):p.69. https://doi.org/10.20527/jbk.v14i1.4587
Wibisono, D. S. and Baziad, A. Description of bone mineral density in postmenopausal women at immunoendocrinology integrated laboratory, faculty of medicine university of Indonesia. Medical Journal of Indonesia. 2004;13(1):pp.31-40. https://doi.org/10.13181/mji.v13i1.127
Yunita, E. P., Imananta, F. P. and Suryana, B. P. Efikasi Terapi Bisfosfonat pada Pasien Osteoporosis Primer dan Osteopenia Melalui Pemantauan Skor DMT (Penelitian Dilakukan di Poliklinik Rheumatologi RSUD Saiful Anwar). Majalah Kesehatan. 2017;4(4)
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