A CASE SERIES OF MYOEPITHELIAL CARCINOMA SPINDLE CELL TYPE, CLEAR CELL TYPE, AND PLASMACYTOID TYPE
DOI:
https://doi.org/10.22219/sm.v13i2.5524Abstract
Myoepithelial Carcinoma adalah salah satu keganasan kelenjar liur yang sangat jarang terjadi, dimana terdiri dari komponen sel-sel myoepithelial yang berdifferensiasi sebagai sel spindle, sel jernih (clear), sel epitheloid, sel stelate, maupun sel plasmacytoid. Kami melaporkan 3 kasus myoepithelial carcinoma yang didiagnosis di Rumah Sakit Dr. Soetomo Surabaya dalam kurun waktu 4 tahun terakhir dengan tiga tipe yang berbeda, yaitu; spindle cell type, clear cell type, dan plasmacytoid type. Dua kasus terjadi pada kelenjar parotis, lainnya pada kelenjar submandibula, dimana ketiganya terjadi pada wanita dengan rentang usia 45-76 tahun. Keluhan saat datang berobat adalah timbul benjolan semakin membesar secara perlahan dan tidak menimbulkan nyeri. Hasil pemeriksaan histopatologis menyatakan suatu carcinoma mengesankan myoepithelial carcinoma. Hasil pemeriksaan immunohistokimia smooth muscle actin (SMA) dan S100 mayoritas menunjukkan hasil yang positif, dimana menyokong diagnosis suatu myoepithelial carcinoma
Kata kunci: myoepithelial carcinoma, spindle cell type, clear cell type plasmacytoid type
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